All Things Considered

NPR's afternoon radio newsmagazine, All things Considered presents two hours of breaking news mixed with compelling analysis, insightful commentaries, interviews, and special - sometimes quirky - features. A one-hour edition of the program is available on Saturday and Sunday.
 

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  • Sundays at 6 p.m.

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Shots - Health News
1:04 pm
Wed January 2, 2013

Drug Fulfills Promise Of Research Into Cystic Fibrosis Gene

Kalydeco is one of the first drugs that is effective at combating the root causes of a genetic disease.
Vertex Pharmaceuticals Inc.

Originally published on Wed January 2, 2013 5:53 pm

The promise of genetic medicine is beginning to be fulfilled, but it's been a long, hard slog.

Take the story of Kalydeco. It's designed to treat people with a lung disease called cystic fibrosis. While not quite a cure, the drug is extremely effective for some CF patients.

But the success of Kalydeco has been more than two decades in the making.

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Asia
9:01 am
Wed January 2, 2013

The Tony Soprano Of Karachi: Gangster Or Politician?

Baloch has been the most powerful figure in Karachi's Lyari neighborhood since 2009. His armed men control the area, and police stay away. He's shown here at his home.
Dina Temple-Raston

Originally published on Wed January 2, 2013 5:56 pm

Gangsters have been part of life in Karachi, Pakistan's largest city, for decades. And nowhere is their rule more notorious than in the slums of Lyari, a dusty warren of low-slung tenement houses in the south central part of Karachi.

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Book Reviews
4:21 pm
Tue January 1, 2013

A Story Of Slavery, Loss And Hope In 1850s Ohio

Originally published on Tue January 8, 2013 12:19 pm

In the aftermath of the Compromise of 1850, a controversial bill that included the Fugitive Slave Act, the journey to freedom became increasingly difficult for enslaved people. In Tracy Chevalier's newest novel, Ohio and its intricate network of Underground Railroad activity provides a rich background for this period.

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Shots - Health News
2:24 pm
Tue January 1, 2013

What The Health Law Will Bring In 2013

The majority of what happens on Jan. 1, 2013, is tax increases and cuts in tax deductions to pay for the changes coming in 2014.
iStockphoto.com

Originally published on Tue January 8, 2013 12:19 pm

Most of the really big changes made by the 2010 health law don't start for another year. That includes things like a ban on restricting pre-existing conditions, and required insurance coverage for most Americans. But Jan. 1, 2013, will nevertheless mark some major changes.

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NPR Story
2:07 pm
Tue January 1, 2013

'Cliff' Deal Would End Payroll Tax Holiday

Originally published on Tue January 8, 2013 12:19 pm

Transcript

AUDIE CORNISH, HOST:

In covering this debate, much has been made of income tax rates and where exactly they should be raised. But one fact has gotten far less notice. Starting today, payroll taxes are going up two percentage points for nearly all American workers. NPR's John Ydstie joins us to talk about it. And John, this means lower take-home pay for a lot of workers starting very soon.

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